Maslany will star opposite Tony nominee Thomas Sadoski (HBO's 'The Newsroom') in LaBute's new play about the aftermath of a drunken hookup.
After a sold-out Off-Broadway run this summer, the play will take a new stage, again directed by Austin Pendleton and starring Stephen McKinley Henderson.
In an unusual move, producers decided to cancel an Off-Broadway run and aim their bloody show straight for the Great White Way.
A London production starring Matt Smith of 'Doctor Who' got mixed reviews last year.
Megan Mullally pulled out of a Broadway revival a few years ago, so this will be NYC's first chance to see McNally's comedy about straight couples in a gay milieu since its first Off-Broadway run 23 years ago.